Tallest: 4 · Year
By quarter-hour; stoppage time counts as the 45th or 90th minute.
Tallest: 2 · Minute
Uruguay's matches with known line-ups from their first recorded cap to their last.
| With them | 24 | 13 | 4 | 7 | 45 | 24 | 54.2% |
| Without them | 48 | 24 | 13 | 11 | 77 | 54 | 50% |
| Alberto Rodríguez | Peru | 2 |
| Alexis Sánchez | Chile | 2 |
| Arturo Vidal | Chile | 2 |
| Carlos Lobatón | Peru | 2 |
| Carlos Sánchez | Colombia | 2 |
| Charles Aránguiz | Chile | 2 |
| Claudio Bravo | Chile | 2 |
| Cristián Zapata | Colombia | 2 |
| David Ospina | Colombia | 2 |
| Eduardo Vargas | Chile | 2 |
Finals and qualifying campaigns alike.
| 13 Jun 2016 | v Jamaica | 3–0 | 21′ | — | Winning goal | 1–0 | Copa América 2016 · Group stage |
| 13 Oct 2015 | v Colombia | 3–0 | 87′ | — | Extended lead | 3–0 | FIFA World Cup qualification 2015 |
| 6 Jun 2015 | v Guatemala | 5–1 | 57′ | — | Extended lead | 5–0 | Friendly |
| 5 Sep 2014 | v Japan | 2–0 | 70′ | — | Extended lead | 2–0 | Kirin Challenge Cup 2014 |
| 23 Jun 2013 | v Tahiti | 8–0 | 67′ | pen | Extended lead | 6–0 | Confederations Cup 2013 · Group stage |
| 23 Jun 2013 | v Tahiti | 8–0 | 45′ | — | Extended lead | 4–0 | Confederations Cup 2013 · Group stage |
| 23 Jun 2013 | v Tahiti | 8–0 | 24′ | — | Extended lead | 2–0 | Confederations Cup 2013 · Group stage |
| 23 Jun 2013 | v Tahiti | 8–0 | 2′ | — | Winning goal | 1–0 | Confederations Cup 2013 · Group stage |
| 2 Sep 2011 | v Ukraine | 3–2 | 87′ | — | Winning goal | 3–2 | Friendly |
| 29 Mar 2011 | v Republic of Ireland | 3–2 | 39′ | — | Winning goal | 3–1 | Friendly |
In a recorded line-up, on the scoresheet or booked. “—” where the line-up isn't known.
| 23 Mar 2017 | v Brazil | 1–4 | came on 77′ | 13 | — | — | FIFA World Cup qualification 2017 |
| 6 Sep 2016 | v Paraguay | 4–0 | came on 76′ | 14 | — | — | FIFA World Cup qualification 2016 |
| 13 Jun 2016 | v Jamaica | 3–0 | started, off 74′ | 74 | 1 | — | Copa América 2016 · Group stage |
| 5 Jun 2016 | v Mexico | 1–3 | came on 60′ | 30 | — | — | Copa América 2016 · Group stage |
| 12 Nov 2015 | v Ecuador | 1–2 | started, off 86′ | 86 | — | — | FIFA World Cup qualification 2015 |
| 13 Oct 2015 | v Colombia | 3–0 | came on 72′ | 18 | 1 | — | FIFA World Cup qualification 2015 |
| 8 Oct 2015 | v Bolivia | 2–0 | started, off 62′ | 62 | — | — | FIFA World Cup qualification 2015 |
| 24 Jun 2015 | v Chile | 0–1 | came on 58′ | 32 | — | — | Copa América 2015 · Quarter-final |
| 20 Jun 2015 | v Paraguay | 1–1 | started, off 45′ | 45 | — | Yellow | Copa América 2015 · Group stage |
| 16 Jun 2015 | v Argentina | 0–1 | came on 69′ | 21 | — | — | Copa América 2015 · Group stage |
| 6 Jun 2015 | v Guatemala | 5–1 | came on 45′ | 45 | 1 | — | Friendly |
| 18 Nov 2014 | v Chile | 2–1 | came on 80′ | 10 | — | — | Friendly |
| 10 Oct 2014 | v Saudi Arabia | 1–1 | came on 70′ | 20 | — | — | Friendly |
| 8 Sep 2014 | v South Korea | 1–0 | started, off 78′ | 78 | — | — | Friendly |
| 5 Sep 2014 | v Japan | 2–0 | came on 65′ | 25 | 1 | — | Kirin Challenge Cup 2014 |
| 28 Jun 2014 | v Colombia | 0–2 | came on 67′ | 23 | — | — | FIFA World Cup 2014 · Round of 16 |
| 14 Jun 2014 | v Costa Rica | 1–3 | came on 76′ | 14 | — | — | FIFA World Cup 2014 · Group stage |
| 30 May 2014 | v Northern Ireland | 1–0 | came on 65′ | 25 | — | — | Friendly |
| 23 Jun 2013 | v Tahiti | 8–0 | started | 90 | 4 | — | Confederations Cup 2013 · Group stage |
| 5 Jun 2013 | v France | 1–0 | came on 65′ | 25 | — | — | Friendly |
| 2 Sep 2011 | v Ukraine | 3–2 | — | — | 1 | — | Friendly |
| 19 Jul 2011 | v Peru | 2–0 | came on 70′ | 20 | — | — | Copa América 2011 · Semi-final |
| 4 Jul 2011 | v Peru | 1–1 | came on 78′ | 12 | — | — | Copa América 2011 · Group stage |
| 8 Jun 2011 | v Netherlands | 1–1 | came on 77′ | 43 | — | — | Copa Confraternidad 2011 |
| 29 Mar 2011 | v Republic of Ireland | 3–2 | started, off 84′ | 84 | 1 | — | Friendly |
Caps, goals and cards count what the sources record: line-ups from about 2003 (World Cups from 1970, friendlies from about 2016), and few scorers in older friendlies — so career totals run low.